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COVID-19 Convalescent Plasma (CCP)

By Jenn Bennett on October 27, 2025

Stanford Blood Center (SBC) has received FDA approval under a Biologics License Application (BLA) to manufacture and distribute high-titer COVID-19 Convalescent Plasma (CCP) nationwide. SBC is the first blood center in California and only the second in the United States to achieve this milestone.

This full licensure replaces the previous Emergency Use Authorization (EUA) and ensures continued access to a proven treatment for immunocompromised patients at risk of severe COVID-19.

SBC has been at the forefront of CCP collection and research since early in the COVID-19 pandemic. With this licensure, SBC continues to advance transfusion medicine by ensuring a reliable national supply of high-titer CCP for patients in need.

Clinical Background and Efficacy

Clinical studies, including multiple randomized controlled trials, have shown that high-titer CCP is safe and effective in improving outcomes and reducing mortality among immunocompromised COVID-19 patients, both inpatient and outpatient.

Product Information

  • Product Type: High-titer COVID-19 Convalescent Plasma (CCP)
  • Manufacturing Site: Stanford Blood Center (FDA-licensed facility)
  • Intended Use: Treatment of immunocompromised patients with COVID-19
  • Storage: Frozen plasma, stored at –18°C or colder
  • Shelf Life: Up to 6 months from date of collection
  • Volume: 200–250 mL units
  • Testing: Each unit tested and verified for antibody titer in accordance with FDA guidelines

How to Order

Hospitals and blood centers interested in ordering COVID-19 Convalescent Plasma may complete our order request form.

Fax orders to: (650) 724-5304
Phone: (650) 725-2491

Orders are fulfilled by SBC’s Product Distribution team in accordance with FDA-approved protocols.

Download the Ordering Form (PDF)

Blood donors interested in donating COVID-19 Convalescent Plasma (CCP), click here.

For general program information, contact:
specialdonations@stanford.edu

For media inquiries, contact:
Julie Peachey, Public Relations Officer
media@stanfordbloodcenter.org
(650) 353-1379

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